Partono Thomas, P. Eko Prasetyo
In the industrial era, the rapid increase of entrepreneurial start-ups in the global economy help to create new jobs and economic growth in Indonesia. However, their sustainability is still facing a lot of obstacles and challenges. Therefore, this study, aims to explain the main determinants of sustainable global entrepreneurial start-ups. Data were analyzed using the Global Entrepreneurship Index (GEI) and the multiple correlation-regression experimental as well as the path analysis model. The results showed that technology absorption, human capital, and competition are the three main determinants for building sustainable start-ups and driving the success of global entrepreneurial competitiveness. Meanwhile, the absence of these factors bring about difficulties in attitudes, abilities, and aspirations to achieve successful competitive performance. These determinants providerecommendations and implications for government policies to participate in building and promoting global sustainable entrepreneurial start-ups through the triple helix model.